How did glycine significantly decrease liver injury?
Chronic cholestasic liver diseases lead to liver injury and ultimately progress to portal fibrosis, cirrhosis, and end-stage liver disease requiring liver transplantation. A research group in the US and Germany investigated the effects of (dietary) glycine against oxidant-induced injury caused by bile duct ligation in rats. The study demonstrate that hepatic injury due to BDL is significantly reduced by dietary glycine and glycine decreases liver injury thru a direct effect on hepatocytes.
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